诺贝尔化学奖授予解决生命中分子手性之谜的研究
Henri Kagan 和 Kenso Soai 因发现分子手性微小不对称性如何被放大以产生高度单一的手性分子,从而解释了生命中同手性(homochirality)如何出现而获得 2026 年诺贝尔化学奖。他们的研究表明,手性催化剂可以非线性地放大微小的不平衡,使得几乎只产生一种镜像形式。
为什么重要. 这一突破对于药物开发、材料科学以及理解生命起源至关重要,因为它解释了生物分子如何实现统一的手性,并能够精确合成手性化合物。
Henri Kagan 和 Kenso Soai 因发现分子手性微小不对称性如何被放大以产生高度单一的手性分子,从而解释了生命中同手性(homochirality)如何出现而获得 2026 年诺贝尔化学奖。他们的研究表明,手性催化剂可以非线性地放大微小的不平衡,使得几乎只产生一种镜像形式。
为什么重要. 这一突破对于药物开发、材料科学以及理解生命起源至关重要,因为它解释了生物分子如何实现统一的手性,并能够精确合成手性化合物。
Seventy-one percent of people with cancer in the United States live for at least five years after diagnosis
Kenso Soai of the Tokyo University of Science
Kagan showed how catalysts can amplify a small asymmetry in handedness.
the five-year survival rate for prostate cancer is now nearly 98%
up from 49% in the late 1970s
DNA is right-handed
amino acids are left-handed
the groundbreaking discoveries by Henri Kagan and Kenso Soai have reshaped our understanding of molecular chirality
Henri Kagan of the University of Paris-Sud
prize committee member Peter Somfai said at the press conference.
“Henri Kagan and Kenso Soai have provided a solution to a chemical mystery that is over a century old: how homochirality can emerge spontaneously,” said Heiner…
Today’s Nobel Prize in Chemistry honors Henri Kagan of the University of Paris-Sud and Kenso Soai of the Tokyo University of Science for discovering how chemis…
“Taken together, the groundbreaking discoveries by Henri Kagan and Kenso Soai have reshaped our understanding of molecular chirality, how it is created, amplif…
In experiments in the 1980s, Kagan showed how to manipulate reactions so that a tiny asymmetry in handedness can be amplified. And in the 1990s, Soai demonstra…